Diabetes Complications 2018-12-18T11:04:15+00:00

The impact of the global epidemic of Type 2 diabetes is staggering; the number of patients will increase from 26 million today to 55 million by 2030.  While there has been an explosion in costs and available treatments to lower glucose, the majority of patients remain suboptimally controlled and therefore 70% of patients will develop one or more complications of diabetes  Chronic inflammation with resultant tissue damage is a primary pathophysiologic factor in the development of the multiple complications including damage to the nerves (neuropathy), eyes (retinopathy), kidneys (nephropathy), liver (nonalcoholic steatohepatitis [NASH], heart (heart failure), and skin (diabetic ulcers). In the United States, more than $68Billion dollars is spent annually on direct medical cost due to complications of diabetes.

Araim lead compound, Cibinetide, is poised for IND application and first human trials to assess safety and efficacy in Phase 2 for liver disease, nephropathy, heart failure, and wound healing.